Whilst severe, lifestyle-threatening, or lethal respiratory depression can manifest Anytime throughout the usage of oxycodone and acetaminophen tablets, the risk is finest over the initiation of therapy or subsequent a dosage raise.

May lead to drowsiness or impair reaction competencies and influence an individual's ability to push or function machinery (oxycodone ingredient). Stay away from Liquor as The mixture may perhaps increase the threat of sedation along with other perhaps deadly Unwanted effects.

Examine the Medication Guidebook furnished by your pharmacist before you start using oxycodone/acetaminophen and every time you will get a refill. Should you have any issues, talk to your doctor or pharmacist.

Infants born to mothers physically depending on opioids may even be bodily dependent and could exhibit respiratory troubles and withdrawal signals [see Safety measures; PREGNANCY].

Tend not to use with almost every other drug containing acetaminophen with no asking your doctor or pharmacist initially. Acetaminophen is in several nonprescription and prescription prescription drugs (for instance ache/fever medication or cough-and-chilly solutions).

To reduce the risk of respiratory melancholy, appropriate dosing and titration of oxycodone and acetaminophen tablets are essential [see DOSAGE AND ADMINISTRATION].

The concomitant use of opioids with other opioid analgesics, for example butorphanol, nalbuphine, pentazocine, may well decrease the analgesic result of oxycodone and acetaminophen tablets and/or precipitate withdrawal signs or symptoms.

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Consider your prescribed dose each and every 6 several hours as desired for pain. Tend not to just take in excess of your prescribed dose. When you overlook a dose, more info get your future dose at your typical time.

To learn about the readily available strengths from the generic and brand-identify versions of oxycodone, see the chart inside the “FAQs about Value and oxycodone” area higher than.

Prolonged utilization of oxycodone more info and acetaminophen tablets during pregnancy can lead to neonatal opioid withdrawal syndrome, which may be daily life-threatening if not identified and treated, and requires administration In line with protocols developed by neonatology professionals.

Think about prescribing naloxone, depending on the individual's chance elements for overdose, including concomitant use of CNS depressants, a record of opioid use dysfunction, or prior opioid overdose.

emphasize to people as well as their caregivers the importance of studying the Medication Tutorial anytime it is actually furnished by their pharmacist, and